Selective Serotonin Reuptake Inhibitor – SSRI
SSRI is the most widely prescribed antidepressant in many countries. Anxiety disorders, personality disorders and depression are often treated with the prescribed drug Selective Serotonin Reuptake Inhibitors (SSRI). SSRI is a psychotropic drug and uses the process called rational drug design. The process involves creating a molecule affecting a specific biological target.
If you have been injured while using a Selective Serotonin Reuptake Inhibitor, you are entitled to reimbursement for your harms and losses. Contact an SSRI lawyer today to discuss your birth defect or depression case.
Names of Popular SSRI Medications
Medical Uses of SSRI
SSRI is mainly used for clinical depression. The drug is frequently prescribed for depersonalization disorder, eating disorders, posttraumatic disorder, chronic pain, social anxiety and obsessive-compulsive disorder. The chemical synapse is located between two nerve cells. Messages go from the one nerve cell to the other nerve cell through the gap (chemical synapse). During the transmission of the messages, serotonin and neurotransmitters are released into the chemical synapse. The recipient cell accepts the neurotransmitters and relays the signal.
SSRI inhibits the reabsorption of neurotransmitters and serotonin by the nerve cells that produced it, which causes the serotonin to stay longer in the small gap between the cells and may repeatedly fuel the receptors of the recipient cell. Research found that the antidepressants activity of SSRI may be misdirected.
SSRI appears to increase the risk of bleeding. SSRI is also associated with an increased rate of birth defects, miscarriages, persistent pulmonary hypertension of a newborn, newborn behavioural syndrome and long term behavioural problems.
SSRI – Newborn Babies
In 2003, there were ninety-three reported cases of withdrawal syndrome in newborn babies. A Lancet study found that doctors should avoid prescribing SSRI to pregnant women with psychiatric disorders. It was also found that some mothers taking SSRI during pregnancy gave birth to babies who developed PPHN (pulmonary hypertension) shortly after birth. Pulmonary hypertension is a serious and life-threatening lung condition. The condition occurs as a result of high pressure in the lung blood vessels. The result of this condition is a lack of oxygen in the bloodstream.
Research was done in five Nordic countries, which included 1.6 million live births of women using the SSRI drug. The study indicated an increased risk of PPHN. The increased risk of PPHN included the SSRI class of drugs, such as Fluoxetine, Sertraline, Citalopram, Paroxetine and Escitalopram. Maternal SSRI use may also be linked with autism.
FDA Safety Announcement
In 2004 the Medicines and Healthcare products Regulatory Agency in the United Kingdom warned the public about the increases in suicide, insomnia, agitation, suicidal thoughts and self-harm in patients treated with SSRI. The Japanese Ministry of Health implemented similar revisions regarding the increased risk of suicidal behaviour in patients younger than 24, and U.S. Food and Drug Administration’s findings resulted in a black box warning. The FDA required the British pharmaceutical company, Glaxo SmithKline, to place a boxed warning on the label of SSRI. A boxed warning is the strongest warning the FDA requires and should indicate that the drug has a significant risk of serious and life-threatening adverse effects.
In 2006, the Food and Drug Administration released a safety announcement based on a single published study, but advised healthcare professionals not to alter current clinical practice of treating depression in pregnant women. In 2011, the Food and Drug Administration received additional study results and concluded that it is too early to reach any conclusion about a possible link between SSRI use in pregnancy and PPHN.
$3 Billion Health-Care Fraud Case
Pharmaceutical fraud consists of activities that result in false claims to insurers or programs for financial gain. Glaxo SmithKline pleaded guilty in July 2012 to criminal charges under the False Claims Act that was related to the illegal promotion of prescription drugs, bribing doctors, its failure to report safety data and for promoting medicines for uses for which they were not licensed. The $3 billion was the largest settlement reached between the United States Department of Justice and a pharmaceutical company from 1991 to 2012.
SSRI Birth Defects Lawsuits
SSRI (Selective Serotonin Reuptake Inhibitor) is a class of antidepressant drug. The drug is mostly used for the treatment of depression and for depersonalization disorders, such as posttraumatic disorder eating disorders, social anxiety, chronic pain and obsessive-compulsive disorder. Side effects that patients can experience include weight gain, dizziness, insomnia and headaches.
The New England Journal of Medicine published studies that were performed in 2006 and 2007. The studies found that SSRI used in women during pregnancy doubled a baby’s risk of being born with omphalocele defects and septal defects. Omphalocele defect occurs when the intestines, liver or other organs remain outside of the abdomen in a sac as a result of a defect in the muscles of the abdominal wall. Septal defect is a defect in the wall dividing the left and right ventricles of the heart.
In the last few years, lawsuits filed against Glaxo SmithKline and other drug manufactures, such as Pfizer, have increased. Lawsuits are filed by mothers who took SSRI while being pregnant and gave birth to babies with related birth defects.
Know Your Rights
We represent all patients and victims involved in SSRI lawsuits. We also handle cases of patients who have suffered side effects of SSRI treatment. Side effects include, but are not limited to, suicide, cardiovascular disease and birth defects.
Time limits apply which may prevent you from being reimbursed for your injury. There are no legal fees unless we are able to recover reimbursement for your harms and losses. Please feel free to contact a SSRI lawyer 24 hours a day, 7 days a week to discuss your case by calling 855-55-BAD-DRUG.